Filtering
Druggability filters utilize traffic light logic to indicate the most crucial protein characteristics
Small molecules
Indicates accessibility of a protein by small molecules
A protein does not belong to a druggable class and does not have small molecules associated
A protein belongs to a druggable class and does not have small molecules associated
A protein is associated with small molecules according to public sources and the PandaOmics manually curated database
Antibodies
Indicates the ability to use antibodies to hit the target
Default status
A secreted or membrane protein without known antibodies
A protein is associated with antibodies according to public sources and the PandaOmics manually curated database
Safety
Potential safety of a target and potential adverse effects
A protein is present in the Essential Genes database and has zerono known small molecules/ antibodies associated
Default status
A protein has known small molecules/antibodies and marked as conditionally/non-essential in Essential Genes database
Novelty
Indicates the overall scientific community interest to the target, based on the volume of related publications proposed by the proprietary AI engine
More than 168 publications
Between 50 and 168 Publications
Less than 50 publications