Affected Pathways

Differentially expressed genes are calculated using the Pandomics's proprietary iPANDA method
Ozerov, I., Lezhnina, K., Izumchenko, E. et al. In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development. Nat Commun 7, 13427 (2016). https://doi.org/10.1038/ncomms13427
The chart represents the grouping of Reactome pathways by the high-level processes affected. Each bar represents the total number of process related pathways divided in three groups:
Significantly activated pathways
Significantly inhibited pathways
Pathways which activity change is not statistically significant across all samples in the case group
Heatmap visualization located below the list of pathways, allows you to assess pathway activation/inhibition across all the samples in the case group