Alex Zhavoronkov, PhD, is the founder and CEO of Insilico Medicine (insilico.com), a leader in generative artificial intelligence technologies for drug discovery and biomarker development. Dr. Zhavoronkov has a combined background in biomedicine and computer technology. He has been recognized by Deep Knowledge Analytics in 2019 as one of the top 100 AI leaders in drug discovery and advanced healthcare globally and has been selected as one of Clarivate's Global Highly Cited Scientists for 2022.

Dr. Zhavoronkov founded Insilico in 2014 and applied AI technologies to analyze a wide range of data types, including anti-aging, disease mechanisms, target identification, and signaling pathway modeling. In 2016, he pioneered the application of key technologies in Generative Adversarial Networks (GANs) and Reinforcement Learning (RL) to drug discovery, discovering novel targets and generating novel molecules with satisfied properties.

Prior to Insilico, Dr. Zhavoronkov worked in senior roles at ATI Technologies (GPU company acquired by AMD in 2006), NeuroGNeuroinformatics, Biogerontology Research Foundation. Since 2012 he published over 200 peer-reviewed research papers, and 3 books. He serves on the advisory or editorial boards of Trends in Molecular Medicine, Aging Research Reviews, Aging, Frontiers in Genetics, npj Agingand co-chairs the Annual Aging Research, Drug Discovery and AI Forum, the world's largest event on aging in the pharmaceutical industry. He is the adjunct professor of artificial intelligence at the Buck Institute for Research on Aging.

Dr. Feng Ren received his Ph.D. degree in chemistry from Harvard University in 2007. He then spent 11 years in the discovery and development of small molecule innovative drugs at GlaxoSmithKline (GSK), where he served as the principal scientist, program leader, director and head of chemistry of Neurodegeneration DPU, a global drug R&D unit in neurosciences in GSK. In 2018, Dr. Ren joined Medicilon, a contract research organization (CRO) providing drug discovery services to the biopharmaceutical companies globally, where he served as senior Vice President and head of the drug R&D service business of the Chemistry Department and Biology Department with over 600 chemists and biologists. In 2021, Dr. Ren joined Insilico Medicine as CSO, responsible for internal pipelines and external collaborations in drug discovery and development. In his career Dr. Ren successfully developed multiple preclinical candidate compounds/clinical phase I compounds for the treatment of non-small cell lung cancer, multiple sclerosis, psoriasis, inflammatory bowel disease, Parkinson's disease, and neuropathic pain. Dr. Ren published over 70 peer-reviewed papers and over 100 patents.

Alex Aliper, PhD, is the President of Insilico Medicine. He pioneered the application of AI in multi-omics data for drug discovery and drug repurposing, generative chemistry and generative biology and put an AI-designed drug into human clinical trials. He built a team of over 100 AI engineers that developed state-of-the-art software products for target discovery, small molecule generation and clinical trial outcome prediction, and he has published over 50 peer-reviewed publications. He was recognised as "Top 100 AI Leaders in Drug Discovery and Advanced Healthcare" by Deep Knowledge Analytics. In 2020, Endpoint News selected Alex Aliper as the top 20 under 40 biotechnology executives globally.

Ms. Michelle Chen, Ph.D., is the Chief Business Officer of Insilico Medicine. She has over 20 years of experience in business development, R&D and commercialization. She was the former SVP and head of Corporate Development and Discovery Business Development at WuXi Biologics. She was also the former Executive Director of Business Development, Search and Evaluation at Merck and the biotechnology executive role at Roche. She received her Ph.D. from the University of Washington.

Dr. Sujata Rao, is the Chief Medical Officer of Insilico Medicine. She has over 30 years of experience in extensive clinical development, academic and medical practice. She previously worked at Eli Lilly, and served as a medical director of integrative sciences at Bristol-Myers Squibb. Dr. Rao received her doctor's degree of medicine from the State University of New York in June 1984.

Leo Shi is based in Shanghai, joined Warburg Pincus in 2019 and focuses on investments in the healthcare sector in Asia. Prior to joining Warburg Pincus, he has been working as Senior Director at Temasek China focusing on healthcare investing since 2015. Prior to Temasek China, he was a VP at Warburg Pincus for three years and has also worked at investment banking and consulting industry. Mr. Shi is currently the chairman of HTDK, and serves on the boards of Insilico Medicine, Haihe Biopharma and Zhenshiming Pharmaceutical.

He received a B.A. of Finance from Fudan University.

Mr. Kan Chen is a Principal of Qiming Venture Partners, focusing on healthcare investment.Before joining Qiming Venture Partners, Kan was a senior scientist at Johnson&Johnson discovering innovative cancer medicine. Prior to that, Kan was a group leader at Jiangsu Hengrui Medicine, developing new cancer immunotherapies.Kan earned his PhD degree in Cell Biology from Case Western Reserve University in the U.S. and finished his postdoctoral training in Immunology at Harvard Medical School. He got his bachelor's degree in biological sciences from Fudan University.

After more than 40 years in academia holding positions in chemistry and human genetics & development at Columbia University, molecular biology at the University California Berkeley, and biomedical engineering and pharmacology at Boston University, Dr. Cantor switched to the private sector where he co-founded Sequenom - the company that first commercialized non invasive prenatal testing, and Retrotope, a clinical stage pharmaceutical company using deuterated essential nutrients as drugs.

Michael Levitt is a Nobel Prize-winning biophysicist who has conducted pioneering work on the molecular structure of essential biological compounds. He has made many significant contributions to the study of protein folding and helped to popularise the use of computer modelling in biology.
Amongst the foremost of Michael's numerous scientific achievements is his development of the first computerised model of an enzyme reaction, which was subsequently expanded to simulate more generalised protein dynamics. He has also carried out important research on the modelling of antibodies as well as DNA and messenger RNA — work that has informed practical advances in biomedical science.
Michael has received many honours and awards for his research, including the 2013 Nobel Prize in Chemistry and the 2014 DeLano Award for Computational Biosciences. A member of the US National Academy of Sciences, since 1987 he has been a Professor of Structural Biology at Stanford University.

Dr. Kai-Fu Lee is the Chairman and CEO of Sinovation Ventures and President of Sinovation Venture's Artificial Intelligence Institute. Prior to founding Sinovation in 2009, Dr. Lee was the President of Google China and a senior executive at Microsoft, SGI, and Apple. Dr. Lee received his Bachelor degree from Computer Science from Columbia University, Ph.D. from Carnegie Mellon University, as well as Honorary Doctorate Degrees from both Carnegie Mellon and the City University of Hong Kong. Author of New York Times, Wall Street Journal bestseller AI Superpowers, Dr. Lee is the Co-Chair of Artificial Intelligence Council for World Economic Forum, a Fellow of the Institute of Electrical and Electronics Engineers (IEEE), Times 100 (The Most Influential People of 2013), WIRED 25 Icons, Asian Business Leader 2018 by Asia House, and is followed by over 50 million audience on social media.

Professor Alan Aspuru-Guzik joined Harvard University in 2006. He leads the Aspuru-Guzik Research Group, a theoretical physical chemistry group in the Department of Chemistry and Chemical Biology at Harvard University. Their research focuses on the connections between quantum computation, quantum information, and chemistry; theoretical studies of energy and charge transfer in photosynthetic complexes and renewable energy materials; methods development for electronic structure theory: first-principles methods, density functional theory, and quantum Monte Carlo; and development of the Clean Energy Project, the world's largest distributed computing project for calculating the properties of candidate molecules for organic solar cells.

Dr. Donald Small is Director of the Division of Pediatric Oncology at the Johns Hopkins Kimmel Cancer Center and the Kyle Haydock Professor of Oncology. He holds joint appointments in Pediatrics and Cellular and Molecular Medicine and Human Genetics. He also directs the Johns Hopkins/National Cancer Institute Pediatric Hematology/Oncology Fellowship program.
Dr. Small's laboratory was the first to clone the human FLT3 gene that is the most frequently mutated gene in acute myeloid leukemia (AML) and results in very poor chances of cure for these patients. The investigations of FLT3 led Dr. Small and his team to discover drugs able to inhibit the cancer-generating activity of this important gene. His laboratory showed that a new class of drugs known as tyrosine kinase inhibitors could kill FLT3-affected cells, thus developing one of the earliest molecularly targeted cancer therapies.

Dr Stevan Djuric was head of the global AbbVie Medicinal Chemistry Leadership Team at Abbott and is also responsible for the Discovery Chemistry and Technology organization within their Discovery organization and chemistry outsourcing activities. The group's current efforts are focused on new initiatives in the areas of high throughput synthesis and purification, hit to lead chemistry, chemical biology including target identification proteomics and new enabling technology identification and development. He was named an AbbVie Distinguished Research Fellow in 2015. During his tenure at Abbott Laboratories, Dr Djuric has been a Project Leader for groups in the Immunoscience, Metabolic Disease, and Antiinfective areas. Several of these programs have advanced compounds into clinical development and to the market including Abbott's proprietary rapamycin analog, Zotarolimus, currently licensed to Medtronics for use on their vascular stents, marketed in the United States and Europe. Dr Djuric has over 180 scientific publications, presentations and patents/applications pending.

Bud Mishra is a professor of computer science and mathematics at NYU's Courant Institute of Mathematical Sciences, professor of human genetics at Mt Sinai School of Medicine, and a professor of cell biology at NYU School of Medicine. Bud has a degree in Sciences from Utkal University, in Electronics and Communication Engineering from Indian Institute of Technology (IIT), Kharagpur, and MS and PhD degrees in Computer Science from Carnegie-Mellon University. Bud is also a visiting scholar at CSHL's Center for Quantitative Biology. From 2001-04, he was a professor at the Watson School of Biological Sciences, Cold Spring Harbor Lab (CSHL) and from 2003-2006, a Visiting Professor at Tata Institute of Fundamental Research (TIFR).
Bud is an IIT, Kharagpur Distinguished Alumnus, NYSTAR Distinguished Professor, AAAS Fellow (engineering: robotics, hardware verification and computational biology), IEEE fellow (robotics and automation) and a fellow of the ACM (computational biology and symbolic computation).
His other research activities, outside of computational and systems biology, take place in the newly created Laboratory for Entrepreneurship in Data Sciences (LEDS) focusing on challenges from Finance, Advertising and Ad Technology, Philanthropy, Biomedicine and Engineering. Somewhat immodestly (and with apologies to Albert Arnold "Al" Gore), the laboratory aims to reinvent the Internet of the future.